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代表性研究论文

作者:时间:2016-08-30点击数:

1. Ruosi Yao, Hao Jiang, Yuhui Ma, Liping Wang, Lin Wang, Juan Du, PingfuHou, Yanyan Gao, Li Zhao, Guannan Wang, Yu Zhang, Dong-Xu Liu, Baiqu Huang and Jun Lu*, Protein arginine methyltransferase 7 (PRMT7) induces the epithelial-to-mesenchymal transition and promotes breast cancer metastasis. Cancer Research. 2014, 74(19):5656-5667 (IF:9.284)

2. Jianchao Zhang, Qian Liang, Yang Lei, Min Yao, Lili Li, Xiaoge Gao, Jingxin Feng, Yu Zhang, Hongwen Gao, Dong-Xu Liu, Jun Lu*, and Baiqu Huang*, SOX4 induces epithelial-mesenchymal transition and contributes to breast cancer progression. Cancer Research. 2012, 72(17):4597-4608 (IF:8.65)

3. Li Zhao, Yu Zhang, Yanyan Gao, PengyuGeng, Yang Lu, Xin Liu, Ruosi Yao, PingfuHou, Dongxu Liu, Jun Lu and Baiqu Huang*, JMJD3 promotes SAHF formation in senescent WI38 cells by triggering an interplay between demethylation and phosphorylation of RB protein. Cell Death & Differentiation. 2015, 22(10):1630-1640 ( IF:8.385)

4. Zhongwei Li, Pingfu Hou, Dongmei Fan, Meichen Dong, Musong Ma Hongyuan Li, Ruosi Yao, Yuxin Li, Guannan Wang,Pengyu Geng, Adhanom Mihretab, Dongxu Liu, Yu Zhang, Baiqu Huang*, and Jun Lu*,The degradation of EZH2 mediated by lncRNA ANCRattenuated the invasion and metastasis of breast cancer, Cell Death & Differentiation. 2016, in press ( IF:8.385)

5. Lili Li, Dongxu Liu, Na Zhang, Qian Liang, Jingxin Feng, Min Yao, Jiwei Liu, Xiaoxue Li, Yu Zhang, Jun Lu*, Baiqu Huang*, SHON, a novel secreted protein, regulates epithelial mesenchymal transition through transforming growth factor (TGF)-β signaling in human breast cancer cells, International Journal of Cancer, 2015, 136: 1285-1295( IF:5.531)

6. Qin W, Li X, Xie L, Li S, Liu J, Jia L, Dong X, Ren X, Xiao J, Yang C, Zhou Y, Chen Z*. A long non-coding RNA, APOA4-AS, regulates APOA4 expression depending on HuR in mice. Nucleic Acids Res. 2016 Jul 27; 44(13):6423-33.

7. Chen Z*. Progress and prospects of long noncoding RNAs in lipid homeostasis. Mol Metab. 2015 Dec 29;5(3):164-70.

8. Chen Z, Canet MJ, Sheng L, Jiang L, Xiong Y, Yin L, Rui L. Hepatocyte TRAF3 promotes insulin resistance and type 2 diabetes in mice with obesity. Mol Metab. 2015 Oct 17;4(12):951-60.

9. Chen Z, Morris DL, Lin J, Liu Y, Rui L. SH2B1 in β cells regulates glucose metabolism by promoting β cell survival and islet expansion. Diabetes. 2014, 63 (2), 585-595

10. Chen Z, Sheng L, Shen H, Zhao Y, Wang S, Brink R, Rui L. Hepatic TRAF2 regulates glucose metabolism through enhancing glucagon responses. Diabetes 2012, 61:566-573.

11. Chen Z, Morris DL, Lin J, Liu Y, Rui L. SH2B1 in β cells promotes insulin expression and glucose metabolism in mice. Mol Endocrinol. 2014, 28 (5), 696-705

12. Chen Z, Shen H, Sun C, Yin L, Tang F, Zheng P, Liu Y, Brink R, Rui L. Myeloid Cell TRAF3 Promotes Metabolic Inflammation, Insulin Resistance, and Hepatic Steatosis in Obesity. Am J Physiol Endocrinol Metab. 2015. 308(6):E460-9.

13. Yuan Q#, Chen Z# (co-first author), Santulli G, Gu L, Yang ZG, Yuan ZQ, Zhao YT, Xin HB, Deng KY, Wang SQ, Ji G. Functional role of calstabin 2 in age-related cardiac alterations. Sci Rep. 2014 Dec 11;4:7425.

14. Sheng L, Zhou Y, Chen Z, Ren D, Cho KW, Jiang L, Shen H, Sasaki Y, Rui L., NF-kB-inducing Kinase (NIK) Promotes Hyperglycemia and Glucose Intolerance in Obesity by Augmenting Glucagon Action. Nature medicine. 2012, 18: 943-949

15. Yang N, Zhao B, Rasul A, Qin H, Li J*, Li X*. PIAS1-modulated Smad2/4 complex activation is involved in zinc-induced cancer cell apoptosis. Cell Death Dis. 2013 ;4:e811:1-16.

16. Millimouno FM, Dong J, Yang L, Li J, Li X*. Targeting Apoptosis Pathways in Cancer and Perspectives with Natural Compounds from Mother Nature. Cancer Prev Res. 2014 ;7(11):1081-1107.  

17. Li X*, Zhu C, Tu WH, Yang N, Qin H, Sun Z*. ZMIZ1 preferably enhances the transcriptional activity of androgen receptor with short polyglutamine tract. PLoS One. 2011; 6 (9): e25040.1-12.

18. He L, Wang T, An J, Li X*, Zhang L, Li L, Li G, Wu X, Su Z, Wang C*. Carbon nanodots@zeolitic imidazolate framework-8 nanoparticles for simultaneous pH-responsive drug delivery and fluorescence imaging. Crystengcomm. 2014; 16: 3259-3263.

19. Wang T, Zhang X, Pan Y, Miao X, Su Z, Wang C*, Li X*. Fabrication of doxorubicin functionalized gold nanorod probes for combined cancer imaging and drug delivery. Dalton Trans. 2011; 40 (38): 9789-9794.

20. Rasul A, Di J, Faya Millimouno FM, Malhi M, Tsuji I, Ali M, Li J*, Li X*. Reactive oxygen species mediate Isoalantolactone-induced apoptosis in human prostate cancer cells. Molecules 2013, 18, 9382-9396

21. Rasul AMillimouno FMEltayb WA, Ali MLi J*, Li X*. Pinocembrin: A Novel Natural Compound with Versatile Pharmacological and Biological Activities. BioMed Research International 2013 (2013)379850, 1-9  

22. Rasul, A, Bao R, Malhi M, Zhao B, Tsuji I, Li J, Li X*. Induction of Apoptosis by Costunolide in Bladder Cancer Cells is Mediated through ROS Generation and Mitochondrial Dysfunction. Molecules 2013, 18, 1418-1433

23. Zhao B, Li X*. Altholactone induces reactive oxygen species-mediated apoptosis in bladder cancer T24 cells through mitochondrial dysfunction, MAPK-p38 activation and Akt suppression. Oncol Rep. 2014;31(6):2769-2775.

24. Rasul A, Khan M, Ali M, Li J, Li X*. Targeting Apoptosis Pathways in Cancer  with Alantolactone and Isoalantolactone. Scientifi World J. 2013; 248532:1-9

25. Tissue-Specific Differences in Cytosine Methylation and Their Association with Differential Gene Expression in Sorghum1. 2011,PLANT PHYSIOL,156(1):1-12;

26. Global transgenerational gene expression dynamics in two newly synthesized allohexaploid wheat (Triticum aestivum) lines.2012, BMC BIOL,10(3):1-18;

27. Intrinsic karyotype stability and gene copy number variations may have laid the foundation for tetraploid wheat formation Intrinsic karyotype stability and gene copy number variations may have laid the foundation for tetraploid wheat formation. 2013,P NATL ACAD SCI USA,110(18):19466-19471;

28. Genome-Wide Disruption of Gene Expression in Allopolyploids but Not Hybrids of Rice Subspecies.2014, MOL BIOL EVOL,31(5):1066-1076;

29. Mutation of a major CG methylase in rice causes genome-wide hypomethylation dysregulated genome expression,and seedling lethality,2014, P NATL ACAD SCI USA, 111(29): 10642- 10647;

30. Evolution of physiological responses to salt stress in hexaploid wheat. 2014,P NATL ACAD SCI USA,111(32):11882-11887;

31. Regulation of secondary cell wall biosynthesis by poplar R2R3 MYB transcription factor PtrMYB152 in Arabidopsis.2014, SCIENTIFIC REPORTS,4(5054):1-7;

32. Evolution of the BBAA Component of Bread Wheat during Its History at the Allohexaploid Level. 2014,PLANT CELL,26:2761-2776;

33. A re-evaluation of the homoploid hybrid origin of Aegilops tauschii, the donor of the wheat D-subgenome. 2015,NEW PHYTOLOGIST,208:4-8;

34. Nonuniform gene expression pattern detected along the longitudinal axis in the matured rice leaf.2015, SCIENTIFIC REPORTS ,5:8015-1-5.

35. Wang S, Chang Y, Brian E (2016) Overview of OVATE FAMILY PROTEINS, a novel class of plant-specific growth regulators. Frontiers in Plant Science, 7: 417.

36. Dai X, Zhou L, Zhang W, Cai L, Guo H, Tian H, Schiefelbein J, Wang S (2016) A single amino acid substitution in the R3 domain of GLABRA1 leads to inhibition of trichome formation in Arabidopsis without affecting its interaction with GLABRA3. Plant, Cell & Environment, 39: 897-907.

37. Zheng K, Tian H, Hu Q, Guo H, Yang L, Cai L, Wang X, Liu B, Wang S (2016) Ectopic expression of R3 MYB transcription factor gene OsTCL1 in Arabidopsis, but not rice, affects trichome and root hair formation. Scientific Reports, 6:19254.

38. Tian H, Huo H, Dai X, Cheng Y, Zheng K, Wang X, Wang S (2015) An ABA down-regulated bHLH transcription repressor gene, bHLH129 regulates root elongation and ABA response when overexpressed in Arabidopsis. Scientific Reports, 5:17587.

39. Wang X, Wang X, Hu Q, Dai X, Tian H, Zheng K, Wang X, Mao T, Chen J-G, Wang S (2015) Characterization of an activation-tagged mutant uncovers a role of GLABRA2 in anthocyanin biosynthesis in Arabidopsis. Plant Journal, 83: 300-311.

40. Wang S, Li E, Porth I, Chen J-G, Mansfield SD, Douglas CJ (2014) Regulation of secondary cell wall biosynthesis by poplar R2R3 MYB transcription factor PtrMYB152 in Arabidopsis. Scientific Reports, 4: 5054.

41. Gan L, Xia K, Chen JG, Wang S (2011) Functional characterization of TRICHOMELESS2, a new single-repeat R3 MYB transcription factor in the regulation of trichome patterning in Arabidopsis. BMC Plant Biology, 11:176.

42. Min Wei,Reiko Shinkura, Yasuko Doi, Mikako Maruya, Sidonia Fagarasan, Tasuku Honjo. Mice carrying a knock-in mutation of Aicda resulting in a defect in somatic hypermutation have impaired gut homeostasis and compromised mucosal defense. Nature Immunol., 2011, 12(3): 264-270 (IF=26.008, cover story)

43. Yunpeng Feng*, ArseniosVlassis*, Céline Roques*, Marie-Eve Lalonde, Cristina González-Aguilera, Jean-Philippe Lambert, Sung-Bau Lee, Xiaobei Zhao, Constance Alabert, Jens V Johansen, Eric Paquet, Xiang-Jiao Yang, Anne-Claude Gingras, Jacques Côté, Anja Groth. BRPF3-HBO1 complex regulates replication origin firing and histone H3K14 acetylation.EMBO J,2015, 35 (2): 176–192 (IF=10.43)

44. JakobMejlvang*, Yunpeng Feng*, Constance Alabert, Kai J. Neelsen, Zuzana Jasencakova, Xiaobei Zhao, Michael Lees, AlbinSandelin, Philippe Pasero, Massimo Lopes, Anja Groth. New Histone Supply Regulates Replication Fork Speed and PCNA Unloading. (* Equal contribution).J Cell Biol, 2014, 204 (1): 29-43 (IF=9.83, research highlight)

45. Qi T, Tang W, Wang L, Zhai L, Guo L, Zeng X. G-actin participates in RNA polymerase II-dependent transcription elongation by recruiting positive transcription elongation factor b (P-TEFb). J Biol Chem. 2011;286(17):15171-81.

46. Wang L, Wang M, Wang S, Qi T, Guo L, Li J, Qi W, Ampah KK, Ba X, Zeng X. Actin polymerization negatively regulates p53 function by impairing its nuclear import in response to DNA damage. PLoS One. 2013;8(4):e60179.

47. Qi W, Wang R, Chen H, Wang X, Xiao T, Boldogh I, Ba X, Han L, Zeng X. BRG1 promotes the repair of DNA double-strand breaks by facilitating the replacement of RPA with RAD51. J Cell Sci. 2015;128(2):317-30.

48. Ba X, Bacsi A, Luo J, Aguilera-Aguirre L, Zeng X, Radak Z, Brasier AR, Boldogh I. 8-oxoguanine DNA glycosylase-1 augments proinflammatory gene expression by facilitating the recruitment of site-specific transcription factors. J Immunol. 2014;192(5):2384-94.

49. Batnasan E, Wang R, Wen J, Ke Y, Li X, Bohio AA, Zeng X, Huo H, Han L, Boldogh I, Ba X. 17-beta estradiol inhibits oxidative stress-induced accumulation of AIF into nucleolus and PARP1-dependent cell death via estrogen receptor alpha. Toxicol Lett. 2015 Jan 5;232(1):1-9.

50. Expression Patterns and Potential Biological Roles of Dip2a.Zhang L, Mabwi HA, Palange NJ, Jia R, Ma J, Bah FB, Sah RK, Li D, Wang D, Bah FB, Togo J, Jin H, Ban L, Feng X, Zheng Y.PLoS One. 2015 Nov 25;10(11):e0143284. doi: 10.1371/journal.pone.0143284. eCollection 2015.

51. Large Genomic Fragment Deletions and Insertions in Mouse Using CRISPR/Cas9.Zhang L, Jia R, Palange NJ, Satheka AC, Togo J, An Y, Humphrey M, Ban L, Ji Y, Jin H, Feng X, Zheng Y.PLoS One. 2015 Mar 24;10(3):e0120396. doi: 10.1371/journal.pone.0120396. eCollection 2015.

52. Regulation of renal fibrosis by Smad3 Thr388 phosphorylation.Qu X, Li X, Zheng Y, Ren Y, Puelles VG, Caruana G, Nikolic-Paterson DJ, Li J.Am J Pathol. 2014 Apr;184(4):944-52. doi: 10.1016/j.ajpath.2013.12.003. Epub 2014 Jan 30.

53. Transcriptional profiling of mouse uterus at pre-implantation stage under VEGF repression.Ji Y, Lu X, Zhong Q, Liu P, An Y, Zhang Y, Zhang S, Jia R, Tesfamariam IG, Kahsay AG, Zhang L, Zhu W, Zheng Y.PLoS One. 2013;8(2):e57287. doi: 10.1371/journal.pone.0057287. Epub 2013 Feb 28.

54. Comment on: Elias et al. Adipose tissue overexpression of vascular endothelial growth factor protects against diet-induced obesity and insulin resistance. Diabetes 2012;61:1801-1813.Lu X, Zheng Y.Diabetes. 2013 Jan;62(1):e3. doi: 10.2337/db12-1130. No abstract available.

55. Resistance to obesity by repression of VEGF gene expression through induction of brown-like adipocyte differentiation.Lu X, Ji Y, Zhang L, Zhang Y, Zhang S, An Y, Liu P, Zheng Y.Endocrinology. 2012 Jul;153(7):3123-32.

56. Xing-Da Ju, Ye Guo, Nan-Nan Wang, Ying Huang, Ming-Ming Lai, Yan-Hua Zhai, Yu-Guang Guo, Jian-Hua Zhang, Rang-Juan Cao, Hua-Li Yu, Lei Cui, Yu-Ting Li, Xing-Zhi Wang, Yu-Qiang Ding and Xiao-Juan Zhu*. Both Myosin-10 Isoforms Are Required for Radial Neuronal Migration in the Developing Cerebral Cortex.Cerebral Cortex, 2014, 24: 1259-1268.

57. Mingming Lai, Ye Guo, Jun Ma, Huali Yu, Dong dong Zhao, Wenqiang Fan, Xing da Ju, Muhammad A. Sheikh, Yousra S. Malik, Wencheng Xiong, Weixiang Guo, Xiaojuan Zhu*. Myosin 10 regulates neuronal radial migration through interacting with N-cadherin. Frontiers in Cellular Neuroscience, 2015, 9, 326.

58. Huali Yu, Dong Sun, Nannan Wang, Min Wang, Yongsheng Lan, Wenqiang Fan, Yang Zhao, Weixiang Guo, Xiaojuan Zhu*. Headless Myo10 is a regulator of microtubule stability during neuronal development. Journal of Neurochemistry. 2015, 135: 261-273.

59. Jing Chen, Runzhi Dou, Zhongzhou Yang, Xiaoping Wang, Chuanbin Mao, Xiang Gao*, Li Wang*, The Effect and Fate of Water-Soluble Carbon Nanodots in Maize (Zea mays L.), Nanotoxicology, (2016) 10(6):818-828. (*corresponding author). IF: 7.913

60. Huai Y, Dong S, Zhu Y, Li X, Cao B, Gao X, Yang M*, Wang L*, Mao  C*. Genetically Engineered Virus Nanofibers as an Efficient Vaccine for Preventing Fungal Infection, Adv Healthc Mater. (2016), 5(7):786-94.  IF: 5.760

61. Yueqing Li, Xiaotong Shan, Ruifang Gao, Song Yang, Shucai Wang, Xiang Gao*, Li Wang*, Two IIIf Clade-bHLHs from Freesia hybrida Play Divergent Roles in Flavonoid Biosynthesis and Trichome Formation when Ectopically Expressed in Arabidopsis, Scientific Reports, (2016)| 6:30514 | DOI: 10.1038/srep30514. (*corresponding author). IF: 5.228

62. Shuai Dong, Hongxi Shi, Donghui Cao, Yicun Wang, Xintong Zhang, Yan Li, Xiang Gao*, Li Wang*, Novel nanoscale bacteriophage-based single-domain antibodies for the therapy of systemic infection caused by Candida albicans, Scientific Reports, (2016) | 6:32256 | DOI: 10.1038/srep32256. . IF: 5.228

63. Wei Sun, Lingjie Liang, Xiangyu Meng, Yueqing Li, Fengzhan Gao, Xingxue Liu, Shucai Wang, Xiang Gao* and Li Wang*Biochemical and Molecular Characterization of a Flavonoid 3-O-glycosyltransferase Responsible for Anthocyanins and Flavonols Biosynthesis in Freesia hybridaFront. Plant Sci. (2016) 7:410.(*corresponding author).IF:4.495

64. Yicun Wang†, Zhigang Ju†, Binrui Cao, Xiang Gao, Ye Zhu, Penghe Qiu, Hong Xu, Pengtao Pan, Huizheng Bao, Li Wang,* and Chuanbin Mao*, Ultrasensitive Rapid Detection of Human Serum Antibody Biomarkers by Biomarker-Capturing Viral Nanofibers, ACS NANO, (2015) 9(4): 4475-4483. IF: 13.334

65. Pengtao Pan†, Yicun Wang†, Ye Zhu†, Xiang Gao, Zhigang Ju, Penghe Qiu, Li Wang*, Chuanbin Mao*, Nontoxic virus nanofibers improve the detection sensitivity for the anti-p53 antibody, a biomarker in cancer patients, Nano Research, (2015) 8(11): 3562–3570. IF: 8.893

66. 生物转化猪脑神经节苷脂制备保护心脑血管活性药物 GM-1,吉林省两所五校科技成果转化基金,2000万元,项目负责人:周义发,批准时间:201507.

67. 专利名称:一种具有唾液酸水解酶活性的蛋白质的制备方法;申请日期:20140609日;授权日期:20160217日;专利号:201410254870.1;发明人:周义发,高娟,原野,及莉,台桂花。

68. 专利名称:一种制备单唾液酸四己糖神经节苷脂的方法;申请日期:20140609日;授权日期:20160629日;专利号:201410254826.0;发明人:周义发,高娟,原野,及莉,冷佳益,陈红磊;台桂花。

69. Zheng Y, Ji L, Leng JY, Yuan Y, Chen HL, Gou DX, Gao YF, Zhou YF. Efficient Biotransformation of Polysialogangliosides for Preparation of GM1 by Cellulosimicrobium sp.21. Molecules. 2014;19: 16001-16012.

70. Gao XG, Zhi Y, Sun L, Peng XX, Zhang T, Xue HT, Tai GH, Zou YF.  The inhibitory effects of a Rhamnogalacturonan I (RG-I) domain from ginseng pectin on galectin-3 and its structure-activity relationship. J Biol Chem. 2013; 288(47):33953-33965.

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实验室地址:吉林省长春市人民大街5268号东北师范大学综合实验楼

Key Laboratory of Molecular Epigenetics of MOE.Northeast Normal University.